Epilepsy & Cognition

1. Heart rate variability, quality of life, and sleep quality in patients with epilepsy

   CONCLUSION: We found that low heart rate variability was more common in patients with epilepsy. Quality of life was also highly impaired in drug-resistant epilepsy, and low heart rate variability correlated with low cognition and emotional well-being in patients with epilepsy.

2. Task demands shape network interactions during reading and visual form processing

   Current theories of reading, based largely on lesion studies, propose that left fusiform gyrus (FusG) is a crucial hub linking visual inputs into the perisylvian language system. However, FusG is also involved in visual form processing more generally, raising the question of whether its engagement with language cortex and other relevant brain regions changes according to task demands, and whether this flexibility is linked to reading proficiency. To answer these questions, we exploit a large,...

3. Combination Therapy with Pyridoxine and Arginine Supplementations along with a Lysine-Restricted Diet in Individuals with Pyridoxine-Dependent Epilepsy: A Comprehensive Systematic Review

   CONCLUSIONS: In summary, administration of pyridoxine is highly effective, particularly when combined with AS and an LRD. Triple therapy illustrates promise for improved seizure control and cognitive function, especially when initiated early. Further research is warranted.

4. Tractography from T1-weighted MRI: Empirically exploring the clinical viability of streamline propagation without diffusion MRI

   Over the last few decades, diffusion MRI (dMRI) streamline tractography has emerged as the dominant method forin vivoestimation of white matter (WM) pathways in the brain. One key limitation to this technique is that modern tractography implementations require high angular resolution diffusion imaging (HARDI). However, HARDI can be difficult to collect clinically, limiting the reach of tractography analyses to research cohorts and thus limiting many WM investigations to certain populations and...

5. Left and right vagus nerve stimulation: historical perspectives, clinical efficacy, and future directions

   Neuromodulation has profoundly transformed medical science, offering new treatments for various neurological conditions. Stimulation techniques that target the brain, spinal cord, trigeminal nerve, and vagus nerve (VN) use electrical impulses to modulate neural functions. Among these, vagus nerve stimulation (VNS) is distinguished for its use to stimulate the VN to modulate neural functions. VNS shows promising applications across a wide range of neurological conditions, exemplifying the ongoing...